EnglishEnglish
Home / Products / API / Nicotinamide Riboside Chloride（NRC）

loading

facebook sharing button
twitter sharing button
line sharing button
wechat sharing button
linkedin sharing button
pinterest sharing button
sharethis sharing button
Model: Nutritional Supplement
Brand: KSW
Product Name: Nicotinamide Riboside Chloride（NRC）
Molecular Weight: 290.70000 g/mol
Molecular Formula: C11H15ClN2O5
CAS Number: 23111-00-4
Availability:
Quantity:
Inquire

Nicotinamide Riboside Chloride（NRC）

Nicotinamide riboside chloride is a crystal form of Nicotinamide riboside (NR) chloride which is a nicotinamide adenine dinucleotide (NAD[+]) precursor vitamin. Nicotinamide riboside chloride increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities. Nicotinamide riboside chloride is used in dietary supplements[1].
Product Description
Common NameNicotinamide riboside chloride
CAS Number23111-00-4Molecular Weight290.70000
DensityN/ABoiling PointN/A
Molecular FormulaC11H15ClN2O5Melting PointN/A
MSDSN/AFlash PointN/A
DescriptionNicotinamide riboside chloride is a crystal form of Nicotinamide riboside (NR) chloride which is a nicotinamide adenine dinucleotide (NAD[+]) precursor vitamin. Nicotinamide riboside chloride increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities. Nicotinamide riboside chloride is used in dietary supplements[1].
Related Catalog
Target

SIRT1

SIRT3

In VitroNicotinamide riboside chloride (0.5 nM; 24 hours) reduces the acetylation status of Ndufa9 and SOD2[1]. Western Blot Analysis[1] Cell Line: HEK293T cells Concentration: 0.5 nM Incubation Time: 24 hours Result: Reduced the acetylation status of Ndufa9 and SOD2.
In VivoChronic Nicotinamide riboside chloride (p.o.; 400 mg/kg/day; for 16 weeks) supplementation increases plasma and intracellular NAD[+] content in a tissue-specific manner[1]. Animal Model: 10-week-old C57Bl/6J mice[1] Dosage: 400 mg/kg Administration: p.o.; daily; for 16 weeks Result: Increased plasma and intracellular NAD[+] content in a tissue-specific manner.
References

[1]. Cantó C, et al. The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protectsagainst high-fat diet-induced obesity. Cell Metab. 2012 Jun 6;15(6):838-47

Molecular FormulaC11H15ClN2O5
Molecular Weight290.70000
Exact Mass290.06700
PSA116.89000


Previous: 
Next: 
Nutritional Supplement Nicotinamide Riboside Chloride（NRC） APIs