English Views: 5 Author: Site Editor Publish Time: 2022-05-18 Origin: Site
Keratin is a carotenoid with wide application value. It has coloring and many physiological functions. It can be used in feed, food, chemical industry, medicine and other industries. It has high economic value. Therefore, it is of great significance to study the biological sources and production methods of keratin and the production and development of keratin.
Canthaxanthin, also known as cantharidin and cantharidin, has the molecular formula c40h52o2 and the chemical name is β,β′- Carotene-4,4 '- Dione is a non vitamin a carotenoid. Natural canthaxanthin exists in certain mushrooms, crustaceans, fish, algae, eggs, blood and liver in very small amounts. For the first time, keratin was isolated from edible mushrooms (Cantharellus cinnabarinus). 
As a diketone carotenoid, it is a useful food colorant in the red wavelength range. It can be used for coloring farmed salmon and Macrobrachium prawn. Studies have shown that the ability of carotenoid keratin containing ketone group to inhibit carcinogenesis is better than that of β- Carotene is strong. Experiments have also proved that keratin can significantly increase the contents of cholesterol, total protein, urea acid and glycerol tricarboxylic acid in Turkey blood, which are significantly reduced by aflatoxin, while - carotene does not affect any of the measured blood. Therefore, there is an obvious interaction between keratin and aflatoxin in terms of sarcosine kinase activity, that is, in the presence of aflatoxin, When the content of canthaxanthin increased, the activity of sarcosine kinase decreased. A large number of clinical trials show that keratin and β- The combination of carotene is more effective in the treatment of patients with hematogenous protoporphyria (EPP) and compound light disease (PMLE) than alone β- Carotene is much better. In addition, keratin has photoprotective effect. It is an excellent quencher of charged activated molecules. At the same time, it can also react with ground state molecules. Because of this, it can be used as an lipophilic antioxidant in human body and protect cells and cell structures from being oxidized by oxidants existing in the fat part of cells. Moreover, keratin has immunomodulatory activity and can be used as an immunomodulatory compound in human body. Bacteriological and cytological studies show that keratin has the function of anti mutagenic complex and preventing malignant cell metastasis. Keratin can proliferate T and B lymphocytes in blood, increase the activity of cytotoxic macrophages and T cells in tumor mass, and maintain the macrophage receptor in antigen.
