English Views: 6 Author: Site Editor Publish Time: 2022-01-12 Origin: Site
Scientific research shows that hirudin is the strongest natural antithrombin substance found in the world so far. It has a strong thrombolytic effect and enhances blood fluidity. It is a special natural substance for human cardiovascular and cerebrovascular diseases. The influence and efficacy of hirudin on the human blood system are mainly as follows:
1. Anticoagulant effect: Hirudin can prevent the effect of thrombin on fibrinogen and prevent blood clotting. 20mg hirudin can prevent 400g blood from clotting.
The water extract and alcohol extract of leeches are also the same The sample has a strong antithrombin effect. Foreign reports have reported that hirudin is the strongest antithrombin substance in the world. It has a strong affinity for thrombin and can neutralize thrombin at a very low concentration.
2. Inhibition of platelet aggregation: Long-term studies have confirmed that hirudin extract has a significant inhibitory effect on ADP-induced platelet aggregation in rats. It can also significantly inhibit platelet aggregation in normal people, and has an anti-thrombotic effect.
3. Thrombus-dissolving effect: Leech has a strong fibrinolytic effect on fibrin in vitro, and its activity is significantly higher than that of Danshen and Rhubarb, and it also has fibrinolytic activity in the body. It can significantly shorten the dissolution time (E-T) of rabbit euglobulin, so hirudin can activate the fibrinolytic system and dissolve thrombus. It was also measured that the hirudin extract can reduce the viscosity of whole blood or plasma and the platelet aggregation rate.
4. Effects on blood rheology: Hirudin can reduce the whole blood viscosity and plasma viscosity of rats, and has a significant effect on the whole blood viscosity, red blood cell aggregation index and reduced specific viscosity of normal rats.
