Oleanic Acid

Alias: Angelica sinensis

Chemical Name: (3β)-3-Hydroxyolean-12-en-28-oic acid.

Pharmacological Effects:

1. Reducing liver damage: Oleanolic acid has a significant protective effect on acute and chronic liver damage in rats caused by carbon tetrachloride.

2. Reduce serum alanine aminotransferase activity: Oleanolic acid has a significant effect on lowering the enzyme in acute and chronic hepatitis and liver cirrhosis animals.

3. Decrease serum r-globulin, which is consistent with the reduction of liver-related inflammation seen in histological observation.

4. Promote the regeneration of liver cells: Oleanolic acid can significantly increase the number of mitotic phases in the remaining liver of rats,and has the effect of promoting cell regeneration.

5. Reduce the level of tyrosine in the brain homogenate of cirrhotic rats, which is beneficial to the prevention and treatment of hepatic encephalopathy.

6. Inhibit liver fibrosis: Oleanolic acid can prevent and treat liver cirrhosis.

7. Oleanolic acid has a significant inhibitory effect on mouse mononuclear phagocyte system, phagocytic function of macrophages and experimental arthritis.

8. It has a protective effect on chromosome damage and can also correct protein metabolism disorders