English Sildenafil lxinyangjian, also known as niobium acid sildenafilcitrate, is known as Viagre, and is an oral dose of cyclophosphate (cGMP)-specific type 5 phosphate dilipipipile (PDE5) inhibitors that enhance erectiles. This product mainly has to enhance the role of burgundy, anti-hypertensive, inhibition of heart function and color perception disorders. Clinical treatment indication is impotence, the recommended dose of 50mg, 1h before sex (0.5 to 4h before sex), according to the effect and tolerance of the drug, the dose can be reduced to 25mg or increased to 100mg, the number of times should not be taken more than 1 time a day. Age over 65 years of age, liver or kidney insufficiency and taking other CYP3A4 inhibitors (erythromycin, ketoconazole, etc.) will increase the plasma concentration of sildenafi, starting at a dose of 25 mg, and patients taking ritonavir (AIDS treatment agent) should not exceed 25 mg in 48h. This product is low toxicity, few side effects and mild, good tolerance. Currently, the U.S. Food and Drug Administration (FDA) has approved drugs for the treatment of erectile dysfunction (ED) in sildinafi, valdinafi and danafinha.
Sildenafil xinyangjian alkali is a type 5 phosphate diester enzyme inhibitor drug. During sexual stimulation, the penis sponge body non-adrenaline energy (NANC) neurons and vascular endothelial cells nitric oxide enzyme catalyzes L-arginine synthesis of nitric oxide, nitric oxide activates bird glycoside synthesis increase, thus causing the penis sponge body smooth muscle and penis small artery smooth muscle relaxation, blood injection penis sponge sinuses, so that the penis erection. Neosoloids can cause nerve cells to secrete nitric oxide, by diffusion through the sponge body blood vessels smooth muscle cells, activation of bird nucleotide cyctase, bird nucleotide activation enzyme can catalyze gip growth cgmp, cgmp signal conduction of the second messenger, the active ingredients in the new impotence can promote the accelerated generation of cgmp, so that smooth cgmp increase, thereby obtaining and maintaining erection.
