English Views: 4 Author: Site Editor Publish Time: 2022-07-04 Origin: Site
Thyroid powder is made from the thyroid glands of pigs, cattle, sheep and other edible animals, removes connective tissue and fat, minced, dehydrated, degreased, dried at below 60 °C, and finely ground. It belongs to thyroid hormone drugs and can be prepared into thyroid tablets.
Thyroid powder is a thyroid hormone drug whose main component is thyroid hormone. Thyroid hormones include thyroxine (T4) and triiodothyronine (T3). It has the effect of promoting catabolism (thermogenesis) and anabolism, and has an important impact on the normal metabolism and growth and development of the human Chemicalbook body, and is very important for the development of the central nervous system of infants and young children. It can be used clinically to treat hypothyroidism caused by various reasons.
Thyroid powder is prepared from pig thyroid glands by: thyroid glands of healthy pigs (preferably young pigs), removing surface connective tissue and fat, flushing with water to remove blood, draining, and quickly processing or quick freezing .
Mincing: Use a meat grinder (mesh plate φ2-3mm) to mince the glands into pulp.
Dehydration: vacuum drying or hot air drying and dehydration below 60°C.
Degreasing: Add three times the amount of ether Chemicalbook to the dehydrated glands, stir at intervals, let stand for 24 hours, and filter to obtain degreasing glands.
Drying: Dry the defatted glands in an oven below 60°C.
Grinding and sieving: First, use a powder machine to beat the dried thyroid into 40-60 mesh fine powder, and then use a ball mill to pulverize it into 80 mesh fine powder.
Test and dilution: According to the test results after the sample test, if the iodine content is high, lactose, sucrose, sodium chloride or starch can be added to make the production meet the standard.
1. Maintain growth and development. Thyroid hormones are necessary for the normal growth and development of the human body, and insufficient or excessive secretion of thyroid hormones can cause diseases. When the thyroid function is insufficient, both physical and mental development are affected, which can cause cretinism (creatinism). When the thyroid function is insufficient in adults, it can cause myxedema.
2. Promote metabolism, thyroid hormone can promote the oxidation of substances, increase oxygen consumption, improve basal metabolic rate, increase heat production, but cannot be used well. Hyperthyroidism has symptoms such as heat intolerance and sweating.
3. It has neurological and cardiovascular effects, and the development of the central nervous system in patients with cretinism occurs. Hyperthyroidism occurs when nervousness, irritability, tremors, increased heart rate, increased cardiac output and other phenomena. Thyroid hormones are mainly used in replacement therapy for hypothyroidism because they increase the sensitivity of the heart to catecholamines. Clinical treatment found that a small number of patients may have a series of adverse reactions such as tachycardia, palpitations, angina pectoris, and arrhythmia due to dose intolerance or overdose, especially if the dose is increased too quickly at the initial stage of treatment.
Thyroid powder is suitable for hypothyroidism caused by various reasons.
1. Cretinism: The earlier the treatment of cretinism, the better the effect. If cretinism is diagnosed and treated early, children can develop normally in the future. Otherwise, although the body is developing normally but the intelligence is still low, cretinism should be treated for life.
2. Hypothyroidism: Alternative treatment for hypothyroidism caused by various causes. Start with a small dose and gradually increase to the desired dose. After the condition is stable, the maintenance dose can be used, and a dose suitable for long-term application can be selected. For patients with hypopituitarism, adrenal cortical hormones should be supplemented before the application of thyroxine to prevent adrenal crisis. Myxedema coma patients must be given emergency treatment, first given T3 treatment, and then change to thyroid tablets after the patient is conscious.
3. Simple goiter: Giving an appropriate amount of thyroxine can supplement the deficiency of endogenous thyroid hormone, and at the same time inhibit the secretion of TSH, so as to relieve the hyperplasia and hypertrophy of thyroid tissue.
4. After thyroidectomy: It can be used as an alternative treatment after thyroidectomy. It can inhibit the secretion of TSH and prevent postoperative bleeding. This product is used for patients after thyroid cancer surgery to delay or prevent the recurrence of thyroid cancer.
5. Application in the treatment of hyperthyroidism: prevention of drug-induced hypothyroidism, prevention of goiter and exophthalmos, suitable for moderate and severe hyperthyroidism, children and pregnancy. Thyroid tablets are usually added after the symptoms are relieved after treatment with antithyroid drugs and the thyroid function returns to normal. Thyroxine can feedback inhibit the secretion of TSH, prevent thyroid enlargement, and prevent the recurrence of hyperthyroidism. Thyroxine in the treatment of exophthalmos can block the pituitary from producing exophthalmos-promoting substances and reduce exophthalmos. It is effective in combination with prednisone.
Excessive use of thyroid powder can cause tachycardia, palpitations, angina pectoris, arrhythmia, headache, nervousness, excitement, restlessness, insomnia, skeletal muscle spasm, muscle weakness, tremor, flushing, heat intolerance, diarrhea, vomiting, weight loss, etc. Symptoms resembling hyperthyroidism. Reduction or discontinuation of the drug can make all symptoms disappear.
1. People with allergies should be disabled.
2. Angina pectoris, coronary heart disease and tachyarrhythmias are disabled.
3. Use with caution in patients with arteriosclerosis, cardiac insufficiency, diabetes, and hypertension.
4. Elderly patients with poor cardiovascular function should be used with caution.
5. Pregnant women and lactating women can cause thyroid dysfunction in fetuses and infants, so they should be used with caution.
