Views: 0 Author: Site Editor Publish Time: 2023-06-09 Origin: Site
Methylcobalamin is an endogenous vitamin B12, but it is more easily absorbed by the human body than vitamin B12, and has better conduction to nerves. As can be seen from its name, it contains the metal element cobalt. When methylcobalamin enters the human body, it can act quickly, accelerate the metabolism of folic acid and nucleic acid, and improve the excitability and transmitter levels of nerves, which has a significant effect on the treatment of peripheral neuropathy.
Methylcobalamin is used in the treatment of megaloblastic anemia caused by vitamin B12 deficiency and also in peripheral neuropathy. That is to say, methylcobalamin has two main functions, one is anemia, and it is the treatment of megaloblastic anemia caused by lack of vitamin B12; the other is peripheral neuropathy.
Methylcobalamin is an endogenous vitamin B12, which exists in blood and spinal fluid. Compared with vitamin B12, it has a good effect on improving the conduction of neurons, and can promote nucleic acid-protein-fat metabolism through methyl conversion reactions. As a coenzyme of methionine synthase, it can convert homocysteine into methionine, participate in the process of deoxynucleoside synthesis of thymine, promote nucleic acid and protein synthesis, promote axonal transport and axonal regeneration and The formation of myelin sheaths prevents axonal degeneration and repairs damaged nerve tissue. Vitamin B12 has important physiological functions for the human body, especially in maintaining the health of the nervous system and the health of blood cells.
The specific diseases that methylcobalamin can treat can be divided into the following three types:
1. Neuropathic pain caused by herpes zoster
Shingles is caused by the varicella-zoster virus and is an infectious disease that affects the skin and nerves. This virus is very cunning. After it invades the sensory nerve endings in the skin, it will move along the nerves to the ganglia in the dorsal root of the spinal cord.
The varicella-zoster virus has been dormant until the patient's immunity is weakened, and then it will infect along the sensory nerve, and finally form herpes zoster. During this period, the patient will experience neuralgia such as acupuncture-like, knife-like, electric shock-like, and even affect the normal life of the patient in severe cases.
In the face of this disease, methylcobalamin is commonly used clinically to treat neuralgia caused by herpes zoster virus. It can act on the transmission of transmitters between neurons, repair damaged nerves, and relieve physical symptoms. And when methylcobalamin is used in combination with famciclovir, it can shorten the time of scab formation.
2. Complications of early diabetes: neuropathy
Early complications of diabetes include neuropathy. Although it is a complication, neuropathy can affect the peripheral nerves and central system of the human body. In addition to targeted blood sugar control and disease stabilization, methylcobalamin can also be used in combination with other related drugs to repair damaged nerves in the treatment of neuropathy.
3. Treatment of megaloblastic anemia
Although megaloblastic anemia sounds strange, the cause of the disease is very simple. It is mainly caused by the lack of vitamin B12 or folic acid. Folic acid is the mainstay of treatment for the disease.
As the main member of the vitamin B12 family, methylcobalamin can promote the maturation and division of erythroblasts, increase the number of red blood cells, and improve anemia.
1. Workers engaged in mercury and its compounds should not take this preparation in large quantities for a long time.
2. If it is not effective after taking it for more than one month, there is no need to continue taking it.
3. Avoid repeated injections at the same site, and be especially careful with newborns, premature infants, infants, and young children. Take care to avoid areas with dense nerve distribution. Pay attention to when the needle is inserted, if there is severe pain or blood reflux, the needle should be pulled out immediately, and the injection site should be changed.
4. The safety of the drug for pregnant and lactating women is not yet clear.
5. Elderly patients should reduce the dosage as appropriate due to the decline of physical function.
6. It is easy to decompose when exposed to light during administration. When using it immediately after opening, it should be protected from light. In order to ensure stable storage quality, a blackout protective bag is used, and it is taken out of the blackout protective bag when in use.