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What is centella asiatica?

Views:6     Author:Site Editor     Publish Time: 2021-11-22      Origin:Site

 Introduction of centella asiatica

Centella asiatica, as a Chinese herbal medicine, is the dry whole plant of centella asiatica, a plant of the genus centella of the umbelliferae family. Perennial creeping herb, sweet, pungent, and cool in nature, has the effects of clearing heat and removing dampness, detoxifying and reducing swelling, promoting blood circulation and stopping bleeding. Madecassoside (MC) is one of the main components of the triterpene saponins of centella asiatica extract. Existing studies have shown that it has an intervening effect on neuronal degeneration, and has anti-oxidant, anti-inflammatory, and neuroprotective pharmacological effects. Function. In addition, centella asiatica extract has protective and repairing effects on the skin, so it is also widely used in cosmetics.

asiaticoside in skin care company-Healthewaybio

Skin protection efficacy of herb extract

Skin protection has been reported in studies, because ultraviolet rays stimulate the secretion of stem cell factor, alpha melanocyte stimulating hormone, endothelin, and adrenocorticotropic hormone and stimulate melanocytes to produce melanin, asiaticoside can inhibit inflammation caused by ultraviolet rays reaction to inhibit the synthesis of melanin, the mechanism is to block the release of melanin stimulating factors from keratinocytes, inhibit the production of PGE2 and PEF2α in keratinocytes, and inhibit the expression of COX2 and PAR2 in keratinocytes caused by ultraviolet.

Wound healing efficacy of natural plant extract

Keloids are proliferative scar tissues that exceed the initial damage range due to excessive connective tissue deposition during delayed wound healing. Studies have found that madecassoside has unique pharmacological properties for it, promotes wound healing and reduces scar formation. The mechanism is that madecassoside can significantly inhibit the phosphorylation of agonist protein, P38 mitogen-activated protein kinase and phosphatidylinositol kinase P13K-AKT signaling pathway, but it has effects on human matrix metalloproteinase 13 and extracellular regulatory protein kinase, and 1/2 phosphorylation has little effect.

In summary, the above research shows that madecassoside has obvious skin protection and repair capabilities, and has small adverse reactions, so it is suitable to be added to skin care products.




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